The toothpaste
Guide

UK sensitivity toothpastes by declared ingredient: the category review behind "only S3".

This page is the table behind one sentence: that S3 is the only sensitivity toothpaste on sale in the UK whose published ingredient list carries potassium nitrate, hydroxyapatite and a fluoride salt together (category review of 51 products, September 2026). It lists every sensitivity toothpaste the review could find on the UK shelf in September 2026, 51 with the ingredient list read from the brand's or a retailer's own page and nine that could not be read, grouped by the desensitising active the list actually contains, with the level declared, the fluoride, the base, the price as shown, the source and the date. Read it to check the sentence, or to place the tube in your hand in its family.

What was checked2 peer-reviewed studies, product information as published by each brand and retailer, the Oral Health Foundation

Key points
  • 50 competitor products and S3 have their ingredient list recorded from a brand or retailer page dated 2026-09-10; five are pending because the page publishes no list or the retailer blocks automated reading, and four could not be found on the UK shelf at all.
  • One product in the 51 combines potassium nitrate, hydroxyapatite and a fluoride salt, and it is S3; the nearest is Spotlight's, which pairs hydroxyapatite and fluoride with potassium citrate rather than nitrate.
  • Potassium nitrate with fluoride is common (11 competitors), hydroxyapatite with fluoride is rare (3), and potassium nitrate with hydroxyapatite does not appear in any competitor list.
  • 13 of the 17 hydroxyapatite products carry no fluoride salt at all, and 11 of the 51 recorded products list no water, which is the base bioactive glass and most stannous pastes need.
  • Every row names its source and its raw record, so a reader, a dentist or an answer engine can check any line against the page it came from.

This page compares ingredients and stated actions only, not clinical performance, based on what each brand states about its own formula. Prices and formulations may change; always check the pack.

How was the shelf read?

From the pages the brands and retailers publish, and from nothing else. The review started with the Boots.com search for sensitive toothpaste and with brand-name searches on Boots, then fetched every brand's own UK site; where the brand publishes no ingredient list, as the Haleon and Procter & Gamble UK sites do not, the Boots product page is the source, and where a brand has no UK site, one UK retailer listing with the list in its text was saved beside the brand's page. Each page was saved once, dated, and never edited; the row points to it. Search-engine summaries, ingredient aggregators and review sites were never used as a source of an ingredient list, so a product whose list exists only there is marked pending, not recorded.

The columns are read, not typed. The actives, the fluoride salt, the presence of water and the combinations of actives are computed from the ingredient string by the build script; the level column is the brand's own declared concentration where the page states one and "no" where it does not; the price is the price shown on the day, with the pack size where the page gives one. A product with several actives appears in each of their tables, and the row id is the same in every table.

Which products carry potassium nitrate?

Eleven competitors and S3, and three of the twelve declare the level of the potassium. Potassium nitrate is the nerve-side active: the Oral Health Foundation lists it, with potassium citrate and stannous fluoride, among the ingredients to look for on a sensitivity pack1. Every potassium nitrate list here also carries a fluoride salt, and all but one sit in a water base, because the salt dissolves in water.

Product, as listedBrandRead fromActives in the published listLevel declaredFluoride, as publishedWater in the listPrice as shownRow
Everyday Sensitive ToothpasteBootsBootspotassium nitratenosodium fluoride, 1450 ppmyes£1.00 (100 ml)CR-019
Max White Clinical Sensitive ProtectColgateBootspotassium nitratenosodium monofluorophosphate, 1450 ppmno£8.00 (75 ml)CR-014
Sensitive Instant Relief Multi ProtectionColgateBootspotassium nitrate; zinc saltnosodium fluoride, 1450 ppmyes£4.50 (75 ml)CR-011
Sensitive with Sensifoam Multi ProtectionColgateBootspotassium nitrate; zinc saltnosodium fluoride, 1450 ppmyes£4.00 (75 ml)CR-012
S3 Daily Sensitive ToothpasteS3 Sensitivity Sciencebrand sitepotassium nitrate; potassium chloride; hydroxyapatite (nano); hydroxyapatitepotassium nitrate 5%; nano-hydroxyapatite 10%; biomimetic hydroxyapatite 5%sodium monofluorophosphate, 1450 ppmyes£14.99 (shown reduced from £19.99)CR-028
Complete Protection+ OriginalSensodyneBootspotassium nitratenosodium fluoride, 1450 ppmyes£5.00 (75 ml)CR-007
Daily Care OriginalSensodyneBootspotassium nitratenosodium fluoride, 1450 ppmyes£2.55 (75 ml)CR-006
Pronamel Daily ProtectionSensodyneBootspotassium nitratesodium fluoride 0.315% w/w (1450 ppm fluoride) and potassium nitrate 5% w/wsodium fluoride, 1450 ppmyes£5.50 (75 ml)CR-004
Procare Sensitive ToothpasteSuperdrugSuperdrugpotassium nitratenosodium fluoride, ppm not statedyes£2.00 (75 ml); £1.00 member price shownCR-057
Sensitive ToothpasteTheraBreathnot established (US site; not on the Boots shelf; Amazon UKpotassium nitratepotassium nitrate 5%sodium fluoride, ppm not statedyesnot capturedCR-049
Sensitive Care ToothpasteWakenbrand sitepotassium nitratenosodium fluoride, 1450 ppmyes£6.00 (75 ml)CR-033
Zendium SensitiveZendiumAmazon UK (not on the Boots shelf; brand site blocks non-bropotassium nitrate; zinc saltnosodium fluoride, 1450 ppmyes£17.59 (Amazon listing, pack size as listed)CR-044

six further products carry a different potassium salt, citrate or chloride, without the nitrate:

Product, as listedBrandRead fromActives in the published listLevel declaredFluoride, as publishedWater in the listPrice as shownRow
Ela Mint n-Ha ToothpasteBokanot established (US brand site, $ pricing)potassium chloride; hydroxyapatite (nano)nonone in the listyes$11.62 (as shown)CR-046
Sensitive + Whitening nano-Hydroxyapatite ToothpasteDavidsnot established (US brand site, $ pricing)potassium chloride; hydroxyapatite (nano); calcium carbonatenonone in the listyes$10.95 (as shown)CR-048
Mineralising PasteNurabrand site; Amazon UKpotassium chloride; hydroxyapatite (nano); hydroxyapatite; zinc salt12% hydroxyapatite (nano + biomimetic micro)none in the listyes£25 (Try Once, as shown)CR-035
Complete Care ToothpasteOrdobrand sitepotassium citrate; zinc saltnosodium fluoride, 1450 ppmyesnot captured (page shows bundle prices)CR-034
Sensitivity + Rebuilding Pro ToothpasteSpotlight Oral CareBoots; brand UK sitepotassium citrate; hydroxyapatitenosodium fluoride, 1450 ppmyes£16.00 (100 ml, Boots)CR-027
Restore refillable gel toothpaste (Wild Mint)SURIbrand sitepotassium chloride; hydroxyapatite (nano); hydroxyapatitenonone in the listyes£10.99 (as shown)CR-029

Which carry hydroxyapatite?

16 competitors and S3, in three forms of the mineral and two kinds of tube. Hydroxyapatite is the tooth's own mineral delivered as particles; the list may say hydroxyapatite, hydroxyapatite (nano) or zinc hydroxyapatite, and a brand may declare the form as nano or biomimetic on its page. The split that matters to a buyer is the fluoride column: 13 of these products carry no fluoride salt, and three competitors pair hydroxyapatite with a fluoride salt.

Product, as listedBrandRead fromActives in the published listLevel declaredFluoride, as publishedWater in the listPrice as shownRow
ApaCare Toothpaste 75 mlApaCarebrand EU shop (apacare.co.uk redirects to apacare.com)hydroxyapatite; zinc saltnosodium fluoride, ppm not statedyes€4.99 (75 ml)CR-045
PremioApagardAmazon UK and importers (no UK site)hydroxyapatite (nano)nonone in the listyes£15.99 (100 g, Amazon UK)CR-043
Plus Sensitive TeethBiorepairUK retailer (Dental Direct); Amazon UKzinc hydroxyapatitenonone in the listyes£5.99 (75 ml, Dental Direct)CR-041
Ela Mint n-Ha ToothpasteBokanot established (US brand site, $ pricing)potassium chloride; hydroxyapatite (nano)nonone in the listyes$11.62 (as shown)CR-046
Sensitive + Whitening nano-Hydroxyapatite ToothpasteDavidsnot established (US brand site, $ pricing)potassium chloride; hydroxyapatite (nano); calcium carbonatenonone in the listyes$10.95 (as shown)CR-048
Re-mineralising Hydroxyapatite Toothpaste MintDimplesbrand site; UK retailershydroxyapatitenonone in the listyes£8.99 (75 ml)CR-036
Bioniq Repair ToothpasteDr WolffBootshydroxyapatite; zinc saltnonone in the listyes£6.99 (75 ml)CR-024
Bioniq Repair Toothpaste PlusDr WolffBootshydroxyapatite; zinc saltnonone in the listyes£7.99 (75 ml)CR-025
Hydroxyapatite Toothpaste Mint (with fluoride)Georganicsbrand sitehydroxyapatite; calcium carbonatenosodium fluoride, 1350 ppmyes£4.90 (as shown)CR-031
Tooth Armour Toothpaste SerumHismileBoots; brand UK sitehydroxyapatite (nano); zinc saltnonone in the listyes£9.99 (20 ml)CR-026
Karex ToothpasteKarexAmazon UK (brand site is en-de)hydroxyapatitenonone in the listyes£42.90 (4 x 75 ml, Amazon UK)CR-042
Mineralising PasteNurabrand site; Amazon UKpotassium chloride; hydroxyapatite (nano); hydroxyapatite; zinc salt12% hydroxyapatite (nano + biomimetic micro)none in the listyes£25 (Try Once, as shown)CR-035
Hydroxyapatite Toothpaste (Wild Mint)RiseWellbrand site (shows £ pricing)hydroxyapatite; calcium carbonate'a 10% concentration of micro-hydroxyapatite' (faq on the page)none in the listno£9.00 (as shown)CR-047
S3 Daily Sensitive ToothpasteS3 Sensitivity Sciencebrand sitepotassium nitrate; potassium chloride; hydroxyapatite (nano); hydroxyapatitepotassium nitrate 5%; nano-hydroxyapatite 10%; biomimetic hydroxyapatite 5%sodium monofluorophosphate, 1450 ppmyes£14.99 (shown reduced from £19.99)CR-028
Sensitivity + Rebuilding Pro ToothpasteSpotlight Oral CareBoots; brand UK sitepotassium citrate; hydroxyapatitenosodium fluoride, 1450 ppmyes£16.00 (100 ml, Boots)CR-027
Restore refillable gel toothpaste (Wild Mint)SURIbrand sitepotassium chloride; hydroxyapatite (nano); hydroxyapatitenonone in the listyes£10.99 (as shown)CR-029
Hydroxyapatite Peppermint 100 mlTruthpastebrand sitehydroxyapatite; calcium carbonatehydroxyapatite content: 5% / 50,000 ppmnone in the listno£13.95 (as shown)CR-032

Which carry a tubule-blocker: stannous fluoride, a bioactive glass or arginine?

14 products, in three chemistries, and the best-labelled family on the shelf. Stannous fluoride is a fluoride salt that also blocks tubules; calcium sodium phosphosilicate is a bioactive glass sold as NovaMin, with calcium phosphosilicate and fluoro calcium phosphosilicate as its relatives; arginine with calcium carbonate is the Pro-Argin system. The glass reacts with water, so its pastes are built without any, and most of the stannous pastes here are too.

Product, as listedBrandRead fromActives in the published listLevel declaredFluoride, as publishedWater in the listPrice as shownRow
BioMin FBioMinbrand site; Amazon UKfluoro calcium phosphosilicate (BioMin)nofluoride bound in bioactive glass, 530 ppmnonot shown on brand pageCR-030
Sensitive & Gum StrengthColgateBootsstannous fluoride; zinc saltnosodium fluoride, stannous fluoride, 1450 ppmyes£4.50 (75 ml)CR-013
Sensitive Instant Relief Repair + Gentle Whitening (100 ml)ColgateBootsarginine; calcium carbonate; zinc saltarginine 8%sodium monofluorophosphate, 1450 ppmyes£7.00 (100 ml)CR-069
Sensitive Instant Relief Repair + Multi-Protection (100 ml)ColgateBootsarginine; calcium carbonate; zinc saltarginine 8%sodium monofluorophosphate, 1450 ppmyes£7.00 (100 ml)CR-070
Sensitive Repair & Prevent + Gentle WhiteningColgateBootsarginine; calcium carbonate; zinc saltarginine 8.00%sodium monofluorophosphate, 1450 ppmyes£8.00 (75 ml)CR-015
Gum+ Breath & SensitivityCorsodylBootsstannous fluoride; zinc saltstannous fluoride 0.4540% w/w and sodium fluoride 0.0721% w/w (1450 ppm fluoride)sodium fluoride, stannous fluoride, 1450 ppmno£5.55 (75 ml)CR-009
Advanced Sensitivity Protection Calm SensationOral-BBootsstannous fluoride; zinc saltstannous fluoride (1100 ppm fluoride) and sodium fluoride (350 ppm fluoride) in the hazards and cautions blocksodium fluoride, stannous fluoride, 1450 ppmyes£5.50 (75 ml)CR-017
Pro-Expert Sensitive Calm SensationOral-BBootsstannous fluoride; zinc saltstannous fluoride (1100 ppm fluoride) and sodium fluoride (350 ppm fluoride) in the hazards and cautions blocksodium fluoride, stannous fluoride, 1450 ppmyes£2.50 (75 ml)CR-016
Sensitive Formula Fresh MintOZENBootscalcium phosphosilicate (AeroGraft)nosodium monofluorophosphate, 1450 ppmyes£10.00 (75 ml)CR-022
Clinical Repair Active WhiteSensodyneBootscalcium sodium phosphosilicate (NovaMin)calcium sodium phosphosilicate (novamin) 5% w/wsodium fluoride, 1450 ppmno£6.00 (75 ml)CR-005
Rapid Relief (Original)SensodyneBootsstannous fluoridestannous fluoride 0.454% w/wsodium fluoride, stannous fluoride, 1450 ppmno£5.30 (75 ml)CR-003
Repair & Protect (Original / Mint)SensodyneBootscalcium sodium phosphosilicate (NovaMin)nosodium fluoride, 1450 ppmno£4.10 (75 ml)CR-001
Repair & Protect WhiteningSensodyneBootscalcium sodium phosphosilicate (NovaMin)nosodium fluoride, 1450 ppmno£4.00 (75 ml)CR-002
Sensitivity & Gum OriginalSensodyneBootsstannous fluoridestannous fluoride 0.454% w/w and sodium fluoride 0.0721% w/w (1450 ppm fluoride)sodium fluoride, stannous fluoride, 1450 ppmno£6.00 (75 ml)CR-008

Which "sensitive" products carry none of those actives in their published list?

Eight recorded products, and the list is the only way to tell. They are positioned for sensitive gums, worn enamel or gentle cleaning, on calcium carbonate, bicarbonate, calcium silicate or a zinc salt; the word "sensitive" on the front covers all of those. This is not a judgement on the products, only a note that none of the eight ingredient words that mark a desensitising active appears in their lists.

Product, as listedBrandRead fromActives in the published listLevel declaredFluoride, as publishedWater in the listPrice as shownRow
Sensitive Pro (Pro Enamel Sensitive)Arm & HammerBootsnone identifiednosodium fluoride, 1100 ppmno£2.33 (75 ml)CR-018
Sensitive Instant Relief Enamel RepairColgateBootscalcium carbonate; zinc saltnosodium monofluorophosphate, 1450 ppmyes£4.50 (75 ml)CR-010
Enzycal 1450Curaproxbrand UK shopnone identifiednosodium fluoride, 1450 ppmyes£6.45 (75 ml)CR-038
Sensitive Gentle Stain RemovalEuthymolBootscalcium carbonate; zinc saltnosodium monofluorophosphate, ppm not statedyes£3.79 (75 ml)CR-020
Fresh Mint Toothpaste with FluorideGreen Peoplebrand sitecalcium carbonatenosodium fluoride, 1450 ppmyes£4.95 (75 ml)CR-039
Sensitive Gums Gentle MintMarvisBootscalcium carbonatenosodium fluoride, ppm not statedyes£9.00 (75 ml)CR-021
Unflavoured ToothpasteOraNursebrand sitenone identifiednosodium monofluorophosphate, ppm not statedyesnot shownCR-040
Enamel Science Advanced ToothpasteRegenerateBootscalcium silicate + sodium phosphate (NR-5)nosodium monofluorophosphate, 1450 ppmyes£7.00 (75 ml)CR-023

Which combine two of the three actives, and which all three?

Two-of-three is ordinary; three-of-three occurs once. Of the 51 recorded lists, potassium nitrate with a fluoride salt appears in 11 competitor products, hydroxyapatite with a fluoride salt in 3, and potassium nitrate with hydroxyapatite in none; the one list that carries potassium nitrate, hydroxyapatite and a fluoride salt together is S3's, row CR-028. The nearest list is Spotlight Sensitivity + Rebuilding Pro, which pairs hydroxyapatite and sodium fluoride with potassium citrate, a different potassium salt with thinner trial evidence than the nitrate.

CombinationCompetitor products with it in the listRows
Potassium nitrate + fluoride salt11CR-004, CR-006, CR-007, CR-011, CR-012, CR-014, CR-019, CR-033, CR-044, CR-049, CR-057
Hydroxyapatite + fluoride salt3CR-027, CR-031, CR-045
Potassium nitrate + hydroxyapatite0none
Potassium nitrate + hydroxyapatite + fluoride salt0 competitors; S3CR-028

The pairing matters because the two actives do different jobs. The 2020 network meta-analysis of 125 randomised trials is the one pooled result that speaks to the pairing: potassium together with hydroxyapatite showed large effects against fluoride toothpaste on the tactile and the air stimulus at moderate certainty, and potassium alone was ranked for touch only2. The 2026 network meta-analysis of 93 randomised trials graded each family against a plain fluoride paste at two weeks: high confidence for stannous fluoride, a large but two-trial result for nano-hydroxyapatite, and a small, low-confidence result for potassium3. Neither review is a verdict on any product in these tables; both are the reason the combination column exists.

The base explains the pattern. Bioactive glass needs a water-free tube and potassium nitrate dissolves in water, so the glass pastes and the potassium pastes live in different tubes; S3's water base is what lets potassium nitrate and hydroxyapatite share one. The Journal's page on how sensitive toothpastes work explains the two jobs from the other direction.

What could not be read, and what was not found?

Five products are pending and four were not found, and this page does not guess at either. Pending means a product exists on the UK market but its ingredient list could not be read from a permitted page on the day: the brand publishes no list in page text, or the retailer refuses automated readers, as Superdrug's category pages and the supermarket sites did. Not found means the review searched the Boots shelf and the brand's UK site and found no sensitivity variant on sale in the UK.

ProductBrandStatusWhyRow
Pärla Pro toothpaste tabsPärlapendingFull INCI not published in the brand page text or the Waitrose page text (accordion empty in a rendered browser). By the brand's own words:CR-037
Nano-Hydroxyapatite ToothpasteFyggpendingFull INCI not published in the page text (checked static and rendered). Fluoride-free by the brand's statement.CR-050
Mint Toothpaste 120 mlGutologypendingPage text names hydroxyapatite and 'fluoride free' but publishes no INCI; not reachable in the rendered browser (domain not permitted). NeedCR-051
Enamel Saver / Tooth BuilderSquiglependingBrand site pages carry no ingredient list in their text. Not counted.CR-052
Sensitive toothpasteTesco / Sainsbury'spendingBoth return HTTP 403 to non-browser clients; tesco.com not permitted in the session browser; Ocado search redirects to its category root. NeCR-058
Sensitive ProfessionalElmexnot foundelmex.co.uk TLS error; Boots search returned no elmex products. The UK equivalent (Pro-Argin) is Colgate Sensitive Repair & Prevent (recordeCR-053
SensitiveAquafreshnot foundOnly US listings found (Aquafresh Sensitive Maximum Strength, potassium nitrate 5%); not recorded as a UK product.CR-054
SensitiveCrestnot foundCrest is not distributed in UK pharmacy retail; Amazon UK search pages blocked non-browser clients.CR-055
Sensitive (no such variant found)Kingfishernot foundKingfisher sells Mint fluoride / fluoride-free pastes (calcium carbonate base); no 'Sensitive' SKU found. INCI not taken from third-party reCR-056

A row moves from pending to recorded when a permitted page with the list is read; the date on the row changes with it, and so does the count in the first paragraph.

How do you check a row yourself?

Open the source named in the row and read the ingredient list on it. Every recorded row carries the URL it was read from and the name of the saved copy, with the date it was read; the saved copy is the review's evidence and the live page is yours. If the live list differs from the row, the pack has been reformulated since the read, which is exactly what the pack-may-change line at the top of this page is for, and the row is due a re-read. The eight words that place a product in a family are potassium nitrate, potassium citrate, potassium chloride, stannous fluoride, calcium sodium phosphosilicate, arginine, hydroxyapatite and, for the last family, none of them.

Frequently asked questions

Does "only S3" mean S3 is the best sensitivity toothpaste?

No. It means one thing, which the tables show: among the 51 published ingredient lists the review could read, S3's is the only one with potassium nitrate, hydroxyapatite and a fluoride salt together. This page compares ingredients and stated actions only, not clinical performance, and the two reviews it cites rate families of actives, not products23.

Why are some well-known products missing?

Because their list could not be read from a permitted page, or because no sensitivity variant was found on the UK shelf. Elmex, Aquafresh and Crest sensitivity pastes are sold elsewhere but were not found on sale in the UK; the Superdrug and supermarket own labels are pending because those sites refuse automated readers. A pending row is not a claim that the product lacks anything.

How current is the table?

Every row carries its read date and the saved copy of the page it came from. Formulations change without notice, so a row can be out of date the day after it is read; the pack in your hand is the authority, and this page tells you which eight words to look for on it.

What is a "family", and can a product be in two?

A family is the desensitising active the list contains: potassium nitrate, another potassium salt, hydroxyapatite, a tubule-blocker, or none of those. A list with two actives sits in two tables under the same row id; Spotlight's paste, for instance, appears under the other potassium salts and under hydroxyapatite.

Where S3 sits

In one row: CR-028, the single list in the review that carries potassium nitrate, hydroxyapatite and a fluoride salt together, in a water base. Two hydroxyapatites and 5% potassium nitrate at the dose the placebo-controlled trials used, with 1450 ppm fluoride kept in, as the declared-level column shows. S3 is owned by more than 20 UK dentists, who have put their own money into it.

S3 Sensitivity Science™ pairs potassium nitrate with two hydroxyapatites and adult-strength fluoride in one daily paste.

See the toothpaste

S3 Sensitivity Science™ puts 5% potassium nitrate, 10% nano-hydroxyapatite and 5% biomimetic hydroxyapatite, both as solution, and full adult-strength fluoride into one daily toothpaste. It is built for three actions at once: calming the nerve, strengthening the enamel surface and protecting against further wear. The formulation is patent-pending S3 Repair Technology™, filed as UK application GB2604755.5. More than 20 practising UK dentists own a stake in S3. Read more about S3.

References 3 sources

1
Oral Health Foundation. Sensitive teeth. https://www.dentalhealth.org/sensitive-teeth Accessed 2026-09-10.
2
Martins CC, Firmino RT, Riva JJ, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. Desensitizing toothpastes for dentin hypersensitivity: a network meta-analysis. Journal of Dental Research. 2020;99(5):514-522. doi:10.1177/0022034520903036 Systematic review and network meta-analysis, 125 randomised trials, 12,541 patients.
3
Gormley AJ, Walsh T, Twigg J, Farrugia C, Pollard A, Bullock B, West NX. Dentifrice formulations for the treatment of dentin hypersensitivity: a systematic review and network meta-analysis. Periodontology 2000. 2026. Systematic review and network meta-analysis, 93 randomised trials.